Speciale ‘I Pinguini’ – Il Pediatra n.6/19, pagg. 54-57
Somministrazione di probiotici in epoca perinatale e neonatale: quali evidenze?
Mariella Baldassarre*, Antonio Di Mauro**, Nicola Laforgia***
*Ricercatrice confermata, Dip. di Scienze Biomediche e Oncologia Umana- Sezione di Neonatologia e T.I.N., Università degli Studi “Aldo Moro”, Bari. AOU “Ospedale Policlinico”, Bari. E-mail: mariaelisabetta.baldassarre@uniba.it
**Dottore di Ricerca, Dip. di Scienze Biomediche e Oncologia Umana- Sezione di Neonatologia e T.I.N., Università degli Studi “Aldo Moro”, Bari.
AOU “Ospedale Policlinico”, Bari. E-mail: dimauroantonio@msn.com
*** Direttore U.O.C. di Neonatologia e T.I.N, Dip. di Scienze Biomediche e Oncologia Umana- Università degli Studi “Aldo Moro”, Bari.
AOU “Ospedale Policlinico”, Bari. E-mail: nicola.laforgia@uniba.it
Bibliografia
- Hillman ET, Yao HLT, Nakatsu CH. Microbial Ecology along the Gastrointestinal Tract. Microbes Environ. 2017, 32, 300–313.
- Baldassarre ME, Palladino V, Amoruso A et al. Rationale of Probiotic Supplementation during Pregnancy and Neonatal Period. 2018 Nov 6;10(11). pii: E1693.
- Pickard JM, Zeng MY, Caruso R, Núñez G. Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease. Immunol. Rev. 2017, 279, 70-89.
- Calatayud M, Koren O, Collado MC. Maternal Microbiome and Metabolic Health Program Microbiome Development and Health of the Offspring. Trends Endocrinol Metab. 2019 Sep 4. pii: S1043-2760(19)30156-0.
- Mastromarino P, Capobianco D, Campagna G Correlation between lactoferrin and beneficial microbiota in breast milk and infant’s feces. Biometals. 2014 Oct;27(5):1077-86.
- Toscano M, de Vecchi E, Rodighiero V, Drago L Microbiological and genetic identification of some probiotics proposed for medical use in 2011.J Chemother. 2013 Jun;25(3):156-61.
- Kolacek S, Hojsak I, Canani RB et al. Commercial probiotic products: A call for improved quality control. A Position Paper by the ESPGHAN Working Group for Probiotics and Prebiotics. Pediatr. Gastroenterol. Nutr. 2017, 65, 117–124.
- Baldassarre ME, Bellantuono L, Mastromarino P et al. Gut and Breast Milk Microbiota and Their Role in the Development of the Immune Function. Pediatr. Rep. 2014, 2, 218–226.
- Carabotti M, Maselli MA, Severi C. The gut-brain axis: Interactions between enteric microbiota, central and enteric nervous systems. Ann. Gastroenterol. 2015, 28, 203–209.
- Cryan JF, Dinan TG. Mind-altering microorganisms: The impact of the gut microbiota on brain and behavior. Nat. Rev. Neurosci. 2012, 13, 701–712.
- Roman P, Rueda-Ruzafa L, Cardona D, Cortes-Rodriguez A. Gut brain axis in the executive function of autism spectrum disorder. Behav. Pharmacol. 2018, 29, 654–663.
- Foster JA, McVey Neufeld KA. Gut-brain axis: How the microbiome influences anxiety and depression. Trends Neurosci. 2013, 36, 305–312.
- Amaral FA, Sachs D, Costa VV et al. Commensal microbiota is fundamental for the development of inflammatory pain. Natl. Acad. Sci. USA 2008, 105, 2193–2197.
- Heijtz RD, Wang S, Anuar F et al. Normal gut microbiota modulates brain development and behavior. Proc. Natl. Acad. Sci. USA 2011, 108, 3047–3052.
- Arentsen T, Qian Y, Gkotzis S et al. The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior. Mol. Psychiatry 2017, 22, 257–266.
- De Palma G, Blennerhassett P, Lu J et al. Microbiota and host determinants of behavioural phenotype in maternally separated mice. Commun. 2015, 6, 7735.
- Desbonnet L, Garrett L, Clarke, G. et al. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience 2010, 170, 1179–1188.
- Savignac HM, Tramullas M, Kiely B et al. Bifidobacteria modulate cognitive processes in an anxious mouse strain. Brain Res. 2015, 287, 59–72.
- Leclercq S, Mian FM, Stanisz AM, et al. Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior. Nat Commun.2017 Apr 4;8:15062.
- Slykerman RF, Coomarasamy C, Wickens K et al. Exposure to antibiotics in the first 24 months of life and neurocognitive outcomes at 11 years of age. Psychopharmacology (Berl).2019 May;236(5):1573-1582.
- Drossman DA. Functional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IV. Gastroenterology 2016;150:1262-79.
- Oświęcimska J, Szymlak A, Roczniak W, et al. New insights into the pathogenesis and treatment of irritable bowel syndrome. Adv Med Sci 2017;27;62:17-30.
- Zeevenhooven J, Koppen IJ, Benninga MA. The New Rome IV Criteria for Functional Gastrointestinal Disorders in Infants and Toddlers. Pediatr. Gastroenterol. Hepatol. Nutr. 2017, 20, 1–13.
- Salvatore S, Baldassarre ME, Di Mauro A et al. Neonatal Antibiotics and Prematurity Are Associated with an Increased Risk of Functional Gastrointestinal Disorders in the First Year of Life.J Pediatr. 2019 Sep;212:44-51
- Baldassarre ME, DiMauro A, Mastromarino P et al. Administration of a Multi-Strain Probiotic Product to Women in the Perinatal Period Differentially Affects the Breast Milk Cytokine Profile and May Have Beneficial Effects on Neonatal Gastrointestinal Function Symptoms. A Randomized Clinical Trial. Nutrients 2016, 8, 677.
26. Baldassarre ME, Di Mauro A, Tafuri S et al. Effectiveness and Safety of a Probiotic-Mixture for the Treatment of Infantile Colic: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial with Fecal Real-Time PCR and NMR-Based Metabolomics Analysis
- Sung V, D’Amico F, Cabana MD et al. Lactobacillus reuteri to Treat Infant Colic: A Meta-analysis. Pediatrics 2018, 141, e20171811.
- Fiocchi A, Pawankar R, Cuello-Garcia C et al. World Allergy Organization-McMaster University Guidelines for allergic disease prevention (GLAD-P): Probiotics. World Allergy Organ J. 2015, 8, 4.
- Allen SJ, Jordan S, Storey M et al. Dietary supplementation with lactobacilli and bifidobacteria is well tolerated and not associated with adverse events during late pregnancy and early infancy. Nutr. 2010, 140, 483–488.
- Kuitunen M, Kukkonen K, Savilahti E. Pro and prebiotic supplementation induces a transient reduction in hemoglobin concentration in infants. J. Pediatr. Gastroenterol. Nutr. 2009, 49, 626–630.